Harlequin Ichthyosis is a very rare and severe genetic disorder of skin. At birth, the infants with this disorder have an extremely hard and thick skin of whole body. The skin form white plates separated by deep cracks. The excessive skin formation causes abnormal contraction of eyes, ears, and limbs. The areas of body where normal skin folds, the resultant cracked skin make it easy to be attacked by bacteria and other pollutant, that can cause serious threat of lethal infections.
In this documentary, four girls from two families are followed, who are suffer from Harlequin Ichthyosis; a life-threatening and untreatable severe genetic condition of skin. We can see and feel the difficulties of their families and the exhausted and troublous condition of the girls.